Journal: bioRxiv
Article Title: A multimodal characterization of the human uncinate fasciculus
doi: 10.64898/2026.03.05.708309
Figure Lengend Snippet: Representative micrographs of A) NogoA immunoreactive OLs and B) PDGFRα immunoreactive OPCs. Scale bar = 10 µm. Images were published in Dr. John Kim’s thesis . Bar plots showing groups means ± standard error of the mean for C) OL soma volume and D) OPC soma volume. Bar plots showing groups means ± standard error of the mean for E) OL density and F) OPC density. Scatter plots with trend line showing the relationships between age and G) OL density and H) OPC density. Magenta trend line denotes positive model coefficient for age while blue trend line denotes negative model coefficient for age. Only the age and OL density relationship was statistically significant (p = 0.010).
Article Snippet: After a series of 3 washes in PBS, the tissues were incubated in biotinylated goat anti-rabbit secondary antibody for NogoA (Vector Laboratories BA-1000) and biotinylated horse anti-goat secondary antibody for PDGFRα (Vector Laboratories BA-9500) diluted in blocking buffer for 2 hours at room temperature.
Techniques: